Avoiding the Pitfalls in Targeting TGF-β to Achieve Better Specificity, Reduced Toxicity & More Effective Treatments
Time: 1:01 pm
day: Pre-Conference Day
Details:
The pleiotropic nature of TGF-β means that this cytokine is involved in numerous mechanisms and pathways. As a result, non-specific targeting can lead to severe side effects and toxicities. This workshop aims to gain a more complete understanding of the TGF-β pathways that can help explain and avoid unintended toxicities in therapies, with a broader look into TGF-β family members that could also help find new targets.
This workshop will cover:
- What are all the pathways and mechanisms of pleiotropic TGF-β?
- How can we avoid the unintended toxicities in organs that are responsive to changes in TGF-β signaling?
- What are the other TGF-β family members that are unintentionally targeted?
